假说驱动与无假说：填补 CoQ 生物合成中的空白。
Hypothesis Driven versus Hypothesis-free: Filling the Gaps in CoQ Biosynthesis.
机构信息
Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain.
Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
出版信息
Cell Metab. 2016 Oct 11;24(4):525-526. doi: 10.1016/j.cmet.2016.09.021.
Two independent investigations based on the power of yeast genetics, but using radically different discovery-driven approaches, have solved a long-pursued goal: the understanding of the early steps in CoQ biosynthesis, which may help diagnose CoQ deficiencies of unknown origin (Payet et al., 2016; Stefely et al., 2016).
两项基于酵母遗传学的独立研究，采用了截然不同的、以发现为导向的方法，实现了一个长期追求的目标：即对辅酶 Q 生物合成早期步骤的理解，这可能有助于诊断未知来源的辅酶 Q 缺乏症（Payet 等人，2016 年；Stefely 等人，2016 年）。
Zotero 插件