Department of Materials Science and Engineering, Ocean University of China, Qingdao, 266100, PR China.
Optoelectronic Materials and Technologies Engineering Laboratory of Shandong, Physics Department, Qingdao University of Science and Technology, Qingdao 266100, PR China.
Analyst. 2016 Nov 28;141(24):6515-6520. doi: 10.1039/c6an01856d.
3D NiO/CoO p-p junction foam was fabricated and applied for electrochemical detection of biomarkers. The theoretical model of employing the interfacial potential barrier as an electrochemical tuning factor was explored in depth. The signals of different targets with similar redox properties could be controllably distinguished by depressing or strengthening the potential barrier. The absorbed positively charged molecules would induce negative charges, inciting a decrease of the potential barrier height Φ and resistance, which is an enhanced tuning factor of the electrochemical signal. However, the effects of the absorbed negatively charged molecules went completely in the inverse direction; the resistance increased following by the increased Φ, which is a weakened tuning factor. Furthermore, the optimum adjustive effects of the p-p junction were validated as both the p-type regions are fully exposed. It is a general strategy to solve the difficulty in selective electrochemical detection of an analyte with similar redox properties. The results build a bridge to connect the potential barrier and electrochemical detection.
3D NiO/CoO p-p 结泡沫被制备并应用于生物标志物的电化学检测。深入探讨了利用界面势垒作为电化学调谐因子的理论模型。通过抑制或增强势垒，可以有选择性地区分具有相似氧化还原性质的不同靶标信号。带正电荷的分子被吸附后会诱导产生负电荷，从而降低势垒高度Φ和电阻，这是电化学信号的增强调谐因子。然而，带负电荷的分子的影响则完全相反；电阻增加伴随着 Φ 的增加，这是一个较弱的调谐因子。此外，通过充分暴露 p 型区域，验证了 p-p 结的最佳调节效果。这是解决具有相似氧化还原性质的分析物选择性电化学检测困难的一般策略。该结果为连接势垒和电化学检测搭建了桥梁。
