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缺铁性贫血患者的心肌功能状态及血液流变学特性

[Functional status of the myocardium and rheologic properties of the blood in patients with iron-deficient anemia].

作者信息

Kovalenko V N, Kuz'mina A P

出版信息

Vrach Delo. 1989 May(5):37-9.

PMID:2773428
Abstract

A study is presented of 38 patients with severe iron-deficiency anemia and 70 patients with non-severe iron-deficiency anemia. All patients showed hypotension with a mean arterial pressure from 70.0 to 76.6 mm Hg. With progression of the severity of iron- deficiency anemia the patients exhibited a reduction of the contractile function of the left ventricular myocardium accompanied by a simultaneous dilatation of its cavity. The hyperkinetic type of hemodynamics is considered as a compensatory reaction of the circulation in response to hypoxia while the state of peripheral hemodynamics evidences venous dilatation furthering high minute blood volume utilization of oxygen at the level of hemotissue barrier is disturbed. Correction of the cardiohemodynamic disorders in combination with ferrotherapy improved the contractile function of the myocardium.

摘要

本文介绍了一项针对38例重度缺铁性贫血患者和70例非重度缺铁性贫血患者的研究。所有患者均表现为低血压,平均动脉压在70.0至76.6毫米汞柱之间。随着缺铁性贫血严重程度的进展,患者左心室心肌的收缩功能降低,同时心室腔扩张。高动力型血流动力学被认为是循环系统对缺氧的一种代偿反应,而外周血流动力学状态表明静脉扩张,这进一步加剧了血液在组织屏障水平对氧气的高利用率的紊乱。结合铁疗法纠正心脏血流动力学紊乱可改善心肌的收缩功能。

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