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[儿童支原体与类风湿性关节炎]

[Mycoplasma and rheumatoid arthritis in children].

作者信息

Vul'fovich Iu V, Gorina L G, Mitchenko A F, Goncharova S A, Gamova N A

出版信息

Vestn Akad Med Nauk SSSR. 1989(6):82-4.

PMID:2773569
Abstract

A microbiological and serologic investigation was carried out in 80 children with rheumatoid arthritis (RA) in order to detect Mycoplasma and Ureaplasma as possible causative agents of RA. The antigen of Mycoplasma in question is shown to be detectable in 42.6% of cases more commonly as part of an association of 2 or more species. M. arthritidis and U. urealyticum are the more common findings. Anti-mycoplasma antibodies were detected in 25.7% of the examined children. The role of these Mycoplasma species in RA is discussed, as is the need for etiotropic treatment of mycoplasma rheumatoid arthritis.

摘要

对80名类风湿性关节炎(RA)患儿进行了微生物学和血清学调查,以检测支原体和脲原体是否为RA可能的致病因子。在所研究的病例中,42.6%可检测到相关支原体抗原,且更常见于两种或更多种病原体联合感染的情况。关节炎支原体和解脲脲原体是较常见的检测结果。在25.7%的受检儿童中检测到抗支原体抗体。文中讨论了这些支原体在RA中的作用,以及对支原体类风湿性关节炎进行病因针对性治疗的必要性。

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