Jänisch W, Staneczek W
Institut für Pathologische Anatomie, Bereich Medizin (Charité), Humboldt-Universität zu Berlin.
Zentralbl Allg Pathol. 1989;135(3):235-40.
In 30 years, from 1956 through 1985, 155 primary tumours of the choroid plexus were first reported for entry into the National Cancer Registry of the GDR, with 125 of them having been identified as plexus papillomas and 30 as plexus carcinomas. A total of 30.4 per cent of all plexus papillomas was diagnosed in patients in the first decade of life, half of them during the first year of life. A lateral ventricle was the site from which 78.9 per cent of the plexus papillomas in the first decade were recorded. Among all plexus tumours 39.4 per cent were detected only on postmortem investigation. The number of plexus tumours reported for entry into the National Cancer Registry had continuously grown in the period under review, which, however, did not necessarily suggest increasing incidence of such tumours in the general population. Possible factors of influence are discussed in some detail, for example, completeness of recording. The number of plexus tumours reported in children up to three years of age rose with significance, between 1981 and 1985. This is assumed to have possibly been the consequence of an aetiological factor. The average annual incidence (crude rate) of plexus tumours at GDR level was found to be 0.3 to one million (0.36 among males and 0.25 among females). Reasons are given that might support the assumption that real incidence has been above these values.
在1956年至1985年的30年间，首次报道有155例脉络丛原发性肿瘤进入民主德国国家癌症登记处，其中125例被确定为脉络丛乳头状瘤，30例为脉络丛癌。在所有脉络丛乳头状瘤患者中，30.4%是在生命的第一个十年被诊断出来的，其中一半是在出生后的第一年。在生命的第一个十年里，78.9%的脉络丛乳头状瘤发生于侧脑室。在所有脉络丛肿瘤中，39.4%是在尸检时才被发现的。在所述期间，进入国家癌症登记处的脉络丛肿瘤报告数量持续增加，然而，这并不一定意味着普通人群中此类肿瘤的发病率上升。文中详细讨论了可能的影响因素，例如记录的完整性。1981年至1985年期间，三岁以下儿童报告的脉络丛肿瘤数量显著增加。这被认为可能是一个病因学因素导致的。民主德国层面脉络丛肿瘤的年平均发病率（粗率）为百万分之0.3（男性为0.36，女性为0.25）。文中给出了一些理由，支持实际发病率高于这些数值的假设。
