ASXL1突变在伴有8号染色体三体的新发急性髓系白血病中很常见，并预示不良预后。 - Suppr | 超能文献

相似文献

1

ASXL1 mutations are frequent in de novo AML with trisomy 8 and confer an unfavorable prognosis.ASXL1突变在伴有8号染色体三体的新发急性髓系白血病中很常见，并预示不良预后。

Leuk Lymphoma. 2017 Jan;58(1):204-206. doi: 10.1080/10428194.2016.1179296. Epub 2016 Oct 13.

2

AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients.伴有 8 号染色体获得这一唯一染色体异常的急性髓系白血病（AML）与一种特殊的分子突变模式相关，其中 46.8%的患者存在 ASXL1 突变。

Leuk Res. 2015 Mar;39(3):265-72. doi: 10.1016/j.leukres.2014.11.026. Epub 2014 Dec 16.

3

ASXL1 mutations define a subgroup of patients with acute myeloid leukemia with distinct gene expression profile and poor prognosis: a meta-analysis of 3311 adult patients with acute myeloid leukemia.ASXL1突变定义了一组急性髓系白血病患者，其具有独特的基因表达谱且预后不良：对3311例成年急性髓系白血病患者的荟萃分析

Leuk Lymphoma. 2015 Jun;56(6):1881-3. doi: 10.3109/10428194.2014.974596. Epub 2015 Jan 8.

4

High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration.基于高分辨率全基因组阵列的比较基因组杂交揭示了以8号染色体三体作为唯一细胞遗传学异常的急性髓系白血病和骨髓增生异常综合征病例中的隐匿性染色体变化。

Leukemia. 2006 May;20(5):840-6. doi: 10.1038/sj.leu.2404145.

5

Trisomy 8 in acute myeloid leukemia.急性髓系白血病中的 8 三体。

Expert Rev Hematol. 2019 Nov;12(11):947-958. doi: 10.1080/17474086.2019.1657400. Epub 2019 Sep 26.

6

AML with t(8;21) and trisomy 4: possible involvement of c-kit?伴有t(8;21)和4号染色体三体的急性髓系白血病：c-kit可能受累？

Leukemia. 2003 Sep;17(9):1915; author reply 1915-6. doi: 10.1038/sj.leu.2403066.

7

ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis.ASXL2突变常见于患有t(8;21)/RUNX1-RUNX1T1的儿童急性髓系白血病患者中，且与较好的预后相关。

Genes Chromosomes Cancer. 2017 May;56(5):382-393. doi: 10.1002/gcc.22443. Epub 2017 Feb 14.

8

Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21.伴单独 4、8、11、13 或 21 号染色体三体的急性髓系白血病患者的临床和分子特征。

Leukemia. 2020 Feb;34(2):358-368. doi: 10.1038/s41375-019-0560-3. Epub 2019 Aug 28.

9

ASXL1 mutations in myeloid neoplasms: pathogenetic considerations, impact on clinical outcomes and survival.髓系肿瘤中的ASXL1突变：发病机制考量、对临床结局和生存的影响

Curr Med Res Opin. 2018 May;34(5):757-763. doi: 10.1080/03007995.2016.1276896. Epub 2017 Jan 24.

10

Trisomy 8 as sole anomaly or with other clonal aberrations in acute myeloid leukemia: impact on clinical presentation and outcome.急性髓系白血病中单纯8号染色体三体或伴有其他克隆性畸变：对临床表现和预后的影响。

Leuk Res. 2007 Jan;31(1):67-73. doi: 10.1016/j.leukres.2006.05.017. Epub 2006 Jun 30.

引用本文的文献

1

Prognostic significance of ASXL1 mutations in acute myeloid leukemia: A systematic review and meta-analysis.急性髓系白血病中ASXL1突变的预后意义：一项系统评价和荟萃分析

Caspian J Intern Med. 2024 Spring;15(2):202-214. doi: 10.22088/cjim.15.2.202.

2

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia with hyperdiploid complex karyotype.异基因造血细胞移植治疗复杂染色体核型高倍体急性髓细胞白血病。

Bone Marrow Transplant. 2024 Feb;59(2):264-269. doi: 10.1038/s41409-023-02167-1. Epub 2023 Dec 13.

3

[Clinical features and survival analysis in non-M(3) acute myeloid leukemia patients with ASXL1 gene mutation].