Tranier S, Bougle D, Pottier M, Venezia R
Service d'Explorations fonctionnelles neurologiques, Hôpital Ambroise Paré, Boulogne, France.
Brain Dev. 1989;11(4):215-20. doi: 10.1016/s0387-7604(89)80039-7.
Premature birth induces a profound change in the environmental factors affecting nerve maturation. The proprioceptive sensory and motor nerve conduction velocities (NCV) of the posterior tibial nerve, which reflect peripheral nerve maturation, have been measured in 3 groups of newborns. Two groups of premature (PT) babies, studied when they reached the expected date of birth (group I, gestational age (GA) at birth, 28-31 weeks, n = 8; group II, GA at birth, 32-35 weeks, n = 6) were compared to 9 normal full-term (FT) newborns. As previously shown, the motor NCV of PT babies at a post-conceptional age close to term is similar to that of FT newborns: group I, 22.70 +/- 2.95 m/s (mean +/- SD); group II, 25.90 +/- 4.61 m/s; FT, 25.48 +/- 4.09 m/s. The proprioceptive sensory NCV was significantly lower in group I (21.59 +/- 4.39 m/s) than in group II (31.89 +/- 4.15 m/s) and FT newborns (32.22 +/- 6.56 m/s) (p less than 0.01). Such a delay in maturation could be responsible for the subtle clinical dysfunctions often observed in PT babies.
早产会引起影响神经成熟的环境因素发生深刻变化。已对3组新生儿测量了反映周围神经成熟情况的胫后神经本体感觉和运动神经传导速度（NCV）。将两组早产（PT）婴儿在达到预期出生日期时进行研究（第一组，出生时胎龄（GA）为28 - 31周，n = 8；第二组，出生时GA为32 - 35周，n = 6），并与9名正常足月（FT）新生儿进行比较。如先前所示，孕龄接近足月时PT婴儿的运动NCV与FT新生儿相似：第一组，22.70 +/- 2.95米/秒（平均值 +/- 标准差）；第二组，25.90 +/- 4.61米/秒；FT组，25.48 +/- 4.09米/秒。第一组的本体感觉NCV（21.59 +/- 4.39米/秒）显著低于第二组（31.89 +/- 4.15米/秒）和FT新生儿（32.22 +/- 6.56米/秒）（p < 0.01）。这种成熟延迟可能是PT婴儿中经常观察到的细微临床功能障碍的原因。
