Hwang Bo Hyun, Kim Younglim, Chae Gi-Bong, Moon Suk-Bae
From the Department of Surgery, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, South Korea.
Pediatr Emerg Care. 2017 Nov;33(11):730-734. doi: 10.1097/PEC.0000000000000946.
The use of abdominal computed tomography (ACT) for nontraumatic abdominal pain in the pediatric emergency department is increasing to a remarkable extent, and every effort should be made to select patients who would benefit from ACT. The aim of this study was to investigate the clinical and laboratory predictors of positive CT yield in pediatric patients with nontraumatic abdominal pain.
The medical records of 739 pediatric patients who, between January 2009 and February 2014, underwent ACT for nontraumatic abdominal pain at the emergency department were reviewed retrospectively. These patients were divided into 2 groups: a right lower quadrant (RLQ) pain group and a non-RLQ pain group. The radiology reports were reviewed to determine ACT diagnoses. Univariate and multivariate analysis was performed to elicit independent predictors of positive ACT yield. Equations predicting the probability of positive ACT diagnosis were deduced from the regression equation in both groups.
In the RLQ pain group, the most frequent ACT diagnosis was acute appendicitis, and in the non-RLQ pain group, enteritis was the most frequent diagnosis. In the RLQ pain group, sex, leukocytosis, neutrophil-to-lymphocyte ratio, and elevated C-reactive protein were significant independent predictors for positive ACT diagnosis. The number of synchronous predictor was significantly related to the proportion of positive ACT diagnosis. In the non-RLQ pain group, leukocytosis was the only significant predictor in multivariate analysis.
Factors predicting positive CT yield were sex, leukocytosis, neutrophil-to-lymphocyte ratio, and elevated C-reactive protein in the RLQ pain group and leukocytosis in the non-RLQ pain group.
儿科急诊科使用腹部计算机断层扫描(ACT)诊断非创伤性腹痛的情况正在显著增加,应尽一切努力挑选能从ACT检查中获益的患者。本研究旨在调查非创伤性腹痛儿科患者CT检查阳性结果的临床和实验室预测因素。
回顾性分析2009年1月至2014年2月期间在急诊科因非创伤性腹痛接受ACT检查的739例儿科患者的病历。这些患者分为两组:右下腹(RLQ)疼痛组和非RLQ疼痛组。审查放射学报告以确定ACT诊断结果。进行单因素和多因素分析以找出ACT检查阳性结果的独立预测因素。根据两组的回归方程推导预测ACT诊断阳性概率的公式。
在RLQ疼痛组中,ACT最常见的诊断是急性阑尾炎,在非RLQ疼痛组中,肠炎是最常见的诊断。在RLQ疼痛组中,性别、白细胞增多、中性粒细胞与淋巴细胞比值以及C反应蛋白升高是ACT诊断阳性的显著独立预测因素。同步预测因素的数量与ACT诊断阳性的比例显著相关。在非RLQ疼痛组中,多因素分析显示白细胞增多是唯一显著的预测因素。
预测CT检查阳性结果的因素在RLQ疼痛组为性别、白细胞增多、中性粒细胞与淋巴细胞比值以及C反应蛋白升高,在非RLQ疼痛组为白细胞增多。