Salajeghe Somaie, Babyn Paul, Sarty Gordon E
Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; Department of Medical Imaging, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Magn Reson Imaging. 2017 Feb;36:40-48. doi: 10.1016/j.mri.2016.10.007. Epub 2016 Oct 12.
In B encoded MRI, a realistic non-linear phase RF encoding coil will generate an inhomogeneous B field that leads to spatially dependent flip angles. The non-linearity of the B phase gradient can be compensated for in the reconstruction, but B inhomogeneity remains a problem. The effect of B inhomogeneity on tip angles for conventional, B encoded MRI, may be minimized using composite pulses. The objective of this study was to explore the feasibility of using composite pulses with non-linear RF phase encoding coils and to identify the most appropriate composite pulse scheme.
RF encoded signals were simulated via the Bloch equation for various symmetric, asymmetric and antisymmetric composite pulses. The simulated signals were reconstructed using a constrained least squares method.
Root mean square reconstruction errors varied from 6% (for an asymmetric composite pulse) to 9.7% (for an antisymmetric composite pulse).
An asymmetric composite pulse scheme created images with fewer artifacts than other composite pulse schemes in inhomogeneous B and B fields making it the best choice for decreasing the effects of spatially varying flip angles. This is contrary to the conclusion that antisymmetric composite pulses are the best ones to use for spin echo sequences in conventional, B encoded, MRI.
在B编码磁共振成像(MRI)中,实际的非线性相位射频编码线圈会产生不均匀的B场,导致空间依赖的翻转角。B相梯度的非线性可在重建过程中得到补偿,但B场不均匀性仍是一个问题。对于传统的B编码MRI,使用复合脉冲可将B场不均匀性对翻转角的影响降至最低。本研究的目的是探讨使用复合脉冲与非线性射频相位编码线圈的可行性,并确定最合适的复合脉冲方案。
通过布洛赫方程对各种对称、不对称和反对称复合脉冲模拟射频编码信号。使用约束最小二乘法对模拟信号进行重建。
均方根重建误差从6%(对于不对称复合脉冲)到9.7%(对于反对称复合脉冲)不等。
在不均匀的B场和B*场中,不对称复合脉冲方案产生的图像伪影比其他复合脉冲方案少,使其成为降低空间变化翻转角影响的最佳选择。这与传统B编码MRI中反对称复合脉冲是自旋回波序列最佳选择的结论相反。