Moussaly Elias, Nazha Bassel, Kedia Shiksha, Chang Qing, Forte Frank
Department of Internal Medicine, North Shore LIJ Staten Island University Hospital , Staten Island, NY, USA.
Department of Hematology/Oncology, North Shore LIJ Staten Island University Hospital , Staten Island, NY, USA.
Rare Tumors. 2016 Oct 6;8(3):6485. doi: 10.4081/rt.2016.6485. eCollection 2016 Sep 5.
Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. gene rearrangement is found in half the cases and has a speculative role in pathogenesis. Complete excision remains the treatment of choice. The roles of chemotherapy and radiation are unclear. We report the hospital course of a 33-year-old female who presented to our institution with a posterior neck mass with spinal invasion, diagnosed as myoepithelial cancer. A literature review of these rare tumors is discussed here.
软组织肌上皮肿瘤是一组罕见但多样的肿瘤,涵盖从良性到恶性的病变。它们在头颈部区域的表现并不常见,诊断具有挑战性。鉴于肌上皮癌与良性对应物相比病程更具侵袭性,早期识别至关重要,尽管两者之间的组织病理学区分可能很困难。在半数病例中发现基因重排,其在发病机制中的作用尚属推测。完整切除仍然是首选治疗方法。化疗和放疗的作用尚不清楚。我们报告了一名33岁女性的住院病程,她因后颈部肿块伴脊髓侵犯就诊于我院,被诊断为肌上皮癌。本文讨论了对这些罕见肿瘤的文献综述。