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Immunoproteasome deficiency in non-small cell lung cancer and its relevance to immunotherapy.

作者信息

Kast Juergen

机构信息

The Biomedical Research Centre, University of British Columbia, Vancouver, Canada; Department of Chemistry, University of British Columbia, Vancouver, Canada.

出版信息

J Thorac Dis. 2016 Sep;8(9):E1082-E1086. doi: 10.21037/jtd.2016.08.80.

Abstract
摘要

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本文引用的文献

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Non-small cell lung cancer: current treatment and future advances.
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Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.
Nat Rev Clin Oncol. 2016 Aug;13(8):473-86. doi: 10.1038/nrclinonc.2016.58. Epub 2016 May 4.
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Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.
Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1555-64. doi: 10.1073/pnas.1521812113. Epub 2016 Feb 29.
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Recent considerations in the use of recombinant interferon gamma for biological therapy of atopic dermatitis.
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New Insights into the Function of the Immunoproteasome in Immune and Nonimmune Cells.
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Interferon-γ Inhibits Ebola Virus Infection.
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