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[孕早期用孕马血清促性腺激素(PMSG)处理刺激猪产前发育的实验研究。2. 妊娠第11天用PMSG处理后幼龄母猪激素的分析研究]

[Experimental studies on the stimulation of prenatal development in swine by PMSG treatment in early pregnancy. 2. Analytic studies of hormones in young sows after PMSG treatment on the 11th day of pregnancy].

作者信息

Kanitz E, Lampe B, Kitzig M, Blödow G, Schneider F, Spitschak K

出版信息

Arch Exp Veterinarmed. 1989 May;43(3):359-66.

PMID:2774833
Abstract

Tens gilts received 400 I.U. of Pregmagon on the 11th day of pregnancy (day of KB2 = 1 day of pregnancy), while 8 sows were used as controls. Blood was sampled 4 times a day between the 11th and 25th day of pregnancy, with an indwelling catheter being used. Progesterone, oestradiol-17 beta, and luteinising hormone were radio-immunologically determined. The hormone profiles of pregnant sows were found to differ unambiguously from those of non-pregnant animals for both concentrations and frequencies. They were indicative of close correlations and time links of gonadotrophic and steroid hormones in early pregnancy and in oestrus. PMSG treatment in pregnancy resulted in increase in the oestradiol-17 beta concentration and attenuation in pulsatile luteinising hormone release at the time of implantation. Progesterone concentrations in peripheral blood were not affected by PMSG injection.

摘要

10头母猪在妊娠第11天(KB2日 = 妊娠第1天)接受400国际单位的孕马血清促性腺激素,而8头母猪作为对照。在妊娠第11天至25天期间,每天通过留置导管采集4次血液样本。采用放射免疫法测定孕酮、雌二醇-17β和促黄体生成素。发现妊娠母猪的激素谱在浓度和频率方面与未妊娠动物有明显差异。它们表明了妊娠早期和发情期促性腺激素和类固醇激素之间的密切相关性和时间联系。妊娠期间进行孕马血清促性腺激素处理导致植入时雌二醇-17β浓度升高,促黄体生成素脉冲式释放减弱。外周血中的孕酮浓度不受孕马血清促性腺激素注射的影响。

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