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血液透析儿童的高血压

Hypertension in hemodialyzed children.

作者信息

Ali Shatha Hussain, Assi Salman Hussain, Hussien Fadhil S

机构信息

Department of Pediatrics, College of Medicine, Al-Nahrain University, Baghdad, Iraq.

Imamane Al-Khadhimain Medical City, Baghdad, Iraq.

出版信息

Saudi J Kidney Dis Transpl. 2016 Sep-Oct;27(5):942-949. doi: 10.4103/1319-2442.190849.

Abstract

Hypertension (HTN) is one of the most common sequelae of chronic kidney disease (CKD) in children. Dialysis-related HTN is predominantly caused by chronic volume overload, and as such the blood pressure (BP) can be reduced and/or brought down to normal in a sizable number of patients with improved salt and fluid balance. This study was conducted to assess the prevalence of HTN among children on hemodialysis (HD) and to evaluate the correlation of HTN with some demographic data. This is a prospective study performed on forty pediatric patients with CKD receiving maintenance HD in three centers in Baghdad. HTN was defined as BP ≥95 th percentile for age, height, and sex or use of antihypertensive medications. HTN was recorded in 27 patients on HD (67.5%), while the BP was normal in the other 13 patients (32.5%). There was no significant correlation between HTN and gender, age, or etiology of CKD. Duration of the HD session, number of sessions per week, total duration on HD, and blood flow rate also had no statistical correlation with HTN. Only serum albumin showed a significant correlation with BP.

摘要

高血压(HTN)是儿童慢性肾脏病(CKD)最常见的后遗症之一。与透析相关的高血压主要由慢性容量超负荷引起,因此,在相当一部分盐和液体平衡得到改善的患者中,血压(BP)可以降低和/或降至正常水平。本研究旨在评估接受血液透析(HD)的儿童中高血压的患病率,并评估高血压与一些人口统计学数据的相关性。这是一项对巴格达三个中心40例接受维持性血液透析的CKD儿科患者进行的前瞻性研究。高血压定义为血压≥按年龄、身高和性别计算的第95百分位数或使用抗高血压药物。27例接受血液透析的患者(67.5%)记录有高血压,而其他13例患者(32.5%)血压正常。高血压与性别、年龄或CKD病因之间无显著相关性。血液透析疗程的持续时间、每周的疗程数、血液透析的总持续时间和血流速率与高血压也无统计学相关性。只有血清白蛋白与血压有显著相关性。

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