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一名血液透析患者出现严重的转移性钙化。

Severe metastatic calcifications in a hemodialysis patient.

作者信息

Labidi Jannet, Ariba Yosra Ben, Gabsia Abdelkader Ben, Ajili Faida, Battikh Riadh, Louzir Bassem, Abdelhafidh Nadia Ben, Othman Saleh I

机构信息

Department of Internal Medicine, Military Hospital, Mont Fleury, Tunis, Tunisia.

Intensive Care Unit, Military Hospital, Mont Fleury, Tunis, Tunisia.

出版信息

Saudi J Kidney Dis Transpl. 2016 Sep-Oct;27(5):1037-1042. doi: 10.4103/1319-2442.190884.

Abstract

Tissue calcification is a common complication in patients on continuous hemodialysis (HD) for chronic renal failure; however, severe calcification is unusual. Three distinct clinical types of extraosseous calcifications are found in uremic patients: vascular calcification, periarticular (tumoral) calcification, and visceral calcification (heart, lung, and kidney). We report a case of a young chronic HD patient who presented with extensive metastatic calcifi cations both vascular, visceral specially localized in the lungs, and periarticular with progressively increasing multiple subcutaneous swellings. This evolution was secondary to noncompliance of the patient to the treatment of a malignant hyperparathyroidism with a marked elevation of phosphocalcium product.

摘要

组织钙化是慢性肾衰竭患者持续血液透析(HD)时常见的并发症;然而,严重钙化并不常见。尿毒症患者存在三种不同临床类型的骨外钙化:血管钙化、关节周围(肿瘤性)钙化和内脏钙化(心脏、肺和肾脏)。我们报告一例年轻的慢性血液透析患者,其出现广泛的转移性钙化,包括血管钙化、主要局限于肺部的内脏钙化以及关节周围钙化,并伴有逐渐增多的多发性皮下肿胀。这种病情进展是由于患者未遵医嘱治疗恶性甲状旁腺功能亢进,导致钙磷乘积显著升高所致。

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