[Interactions of detergents with phospholipid bilayers at sublytic concentrations--partition or binding?].

Using the bubble pressure method the interaction of liposomes with detergents at sublytic concentrations was studied. The results are discussed in terms of a partition or binding model. The findings support an equilibrium partition of the surfactant between the aquous and lipid phase. For some detergents, however, concentration dependent partition coefficients were found.