Bayramoğlu A, Bektaş O, Yaman M
Department of Cardiology, Ordu University, Ordu, Turkey.
Herz. 2017 Jun;42(4):418-424. doi: 10.1007/s00059-016-4485-6. Epub 2016 Oct 17.
The aim of this study was to evaluate the relationship between the SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) score and left ventricular end-diastolic pressure (LVEDP) measured with an invasive method and with speckle-tracking echocardiography (STE).
The study included 124 patients who underwent cardiac catheterization. LVEDP values and coronary images were obtained for all patients. SYNTAX scores were calculated and separated into three tertiles (SYNTAX = 0, SYNTAX < 22, and SYNTAX > 22). Standard echocardiography and STE were performed on all the patients. Peak LA strain (LAs strain) in ventricular end-systole and LA strain during LA contraction (LAa strain) values were obtained with STE.
In univariate analysis, a strong correlation was observed between the SYNTAX score and LAs strain and a moderate correlation with LAa strain. A moderate correlation was also found between both LAs strain and LAa strain and LVEDP. In multiple regression analysis, LAs strain and LVEDP were observed to be independent predictors of SYNTAX score.
LAs strain and LVEDP were observed to be independent predictors of SYNTAX scores. The relationship between LAs strain, LVEDP, and SYNTAX score could be useful in clinical practice.
本研究的目的是评估SYNTAX(紫杉醇药物洗脱支架与心脏外科手术协同作用)评分与通过有创方法及斑点追踪超声心动图(STE)测量的左心室舒张末期压力(LVEDP)之间的关系。
该研究纳入了124例行心导管检查的患者。获取了所有患者的LVEDP值和冠状动脉图像。计算SYNTAX评分并将其分为三个三分位数(SYNTAX = 0、SYNTAX < 22和SYNTAX > 22)。对所有患者进行了标准超声心动图和STE检查。通过STE获得心室收缩末期的峰值左心房应变(LAs应变)和左心房收缩期的左心房应变(LAa应变)值。
在单变量分析中,观察到SYNTAX评分与LAs应变之间存在强相关性,与LAa应变存在中度相关性。还发现LAs应变和LAa应变与LVEDP之间均存在中度相关性。在多因素回归分析中,观察到LAs应变和LVEDP是SYNTAX评分的独立预测因素。
观察到LAs应变和LVEDP是SYNTAX评分的独立预测因素。LAs应变、LVEDP和SYNTAX评分之间的关系在临床实践中可能有用。