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高效纳米纤维膜在抗菌伤口敷料和防晒方面的应用。

Efficient Nanofibrous Membranes for Antibacterial Wound Dressing and UV Protection.

机构信息

Max Planck Institute for Polymer Research , Ackermannweg 10, 55128 Mainz, Germany.

Institute of Coal Chemistry, Chinese Academy of Sciences , Taiyuan 030001, China.

出版信息

ACS Appl Mater Interfaces. 2016 Nov 9;8(44):29915-29922. doi: 10.1021/acsami.6b09165. Epub 2016 Oct 31.

Abstract

Materials with a hierarchical structure often demonstrate superior properties with combined and even synergistic effects of multiple functions. Herein, we report the design of a new class of material with a multicompartment nanofibrous structure as a promising candidate for antibacterial wound dressing and functional textile applications. The design consists in first synthesizing nanocapsules loaded with functional payloads and subsequently embedding the nanocapsules into polymer nanofibers by using the colloid-electrospinning technique. The nanocontainer-in-nanofiber structure allows for a selective and separate loading of different functional agents with different polarities, and it offers a flexible combination of the properties of nanocontainers and nanofibers. An example of the potential for these multicompartment materials is demonstrated here, in which the synergistic antibacterial effect against E. coli K-12 and B. Subtilis combined with anti-UV property is shown.

摘要

具有层次结构的材料通常具有优异的性能,具有多种功能的组合甚至协同效应。在此,我们报告了一类具有多隔室纳米纤维结构的新材料的设计,该材料有望成为抗菌伤口敷料和功能性纺织品的候选材料。该设计包括首先合成负载有功能有效成分的纳米胶囊,然后通过胶体静电纺丝技术将纳米胶囊嵌入聚合物纳米纤维中。纳米容器-纳米纤维结构允许对不同极性的不同功能试剂进行选择性和单独负载,并提供纳米容器和纳米纤维性能的灵活组合。在此展示了这些多隔室材料的潜在应用,其中显示了对大肠杆菌 K-12 和枯草芽孢杆菌的协同抗菌作用以及抗 UV 性能。

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