2001年至2013年法国新生儿脑膜炎球菌性脑膜炎
Neonatal Meningococcal Meningitis In France From 2001 To 2013.
作者信息
Bilal Ali, Taha Muhamed-Kheir, Caeymaex Laurence, Cohen Robert, Levy Corinne, Durrmeyer Xavier
机构信息
From the *Service de Neonatalogie, Centre Hospitalier Intercommunal, Créteil, France; †Institut Pasteur, Invasive Bacterial Infections Unit, National Reference Center for Meningococci (NRCM), Paris, France; ‡Clinical Research Center (CRC), Centre Hospitalier Intercommunal de Créteil, Créteil, France; §Groupe de Pathologie Infectieuse Pédiatrique, SFP Société Française de Pédiatrie, Paris, France; ¶Université Paris Est, IMRB- GRC GEMINI, Créteil, France; ‖ACTIV, Association Clinique et Thérapeutique Infantile du Val de Marne, Saint-Maur des Fossés, France; and **Unité Court Séjour, Petits Nourrissons, Service de Néonatalogie, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
出版信息
Pediatr Infect Dis J. 2016 Nov;35(11):1270-1272. doi: 10.1097/INF.0000000000001296.
Among 831 cases of neonatal bacterial meningitis occurring from 2001 to 2013, Neisseria meningitidis was the third most frequent bacterial species found. All cases occurred only in term neonates and were mainly late onset. Serogroup B accounted for 78% of cases. At diagnosis, 27% of cases had at least one sign of disease severity. All strains were susceptible to cefotaxime, but 12% showed intermediate susceptibility to penicillin G and to aminopenicillin.
在2001年至2013年发生的831例新生儿细菌性脑膜炎病例中，脑膜炎奈瑟菌是发现的第三常见细菌种类。所有病例仅发生在足月儿，且主要为晚发型。B群占病例的78%。诊断时，27%的病例至少有一项疾病严重程度的体征。所有菌株对头孢噻肟敏感，但12%对青霉素G和氨基青霉素表现出中介敏感性。
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