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在药物基因组学课程中使用个人基因型数据对学生学习和态度的影响。

Effects of Using Personal Genotype Data on Student Learning and Attitudes in a Pharmacogenomics Course.

作者信息

Weitzel Kristin Wiisanen, McDonough Caitrin W, Elsey Amanda R, Burkley Benjamin, Cavallari Larisa H, Johnson Julie A

机构信息

University of Florida College of Pharmacy, Gainesville, Florida; University of Florida Center for Pharmacogenomics, Gainesville, Florida.

University of Florida Clinical Translational Science Institute, Gainesville, Florida.

出版信息

Am J Pharm Educ. 2016 Sep 25;80(7):122. doi: 10.5688/ajpe807122.

DOI:10.5688/ajpe807122
PMID:27756930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5066925/
Abstract

To evaluate the impact of personal genotyping and a novel educational approach on student attitudes, knowledge, and beliefs regarding pharmacogenomics and genomic medicine. Two online elective courses (pharmacogenomics and genomic medicine) were offered to student pharmacists at the University of Florida using a flipped-classroom, patient-centered teaching approach. In the pharmacogenomics course, students could be genotyped and apply results to patient cases. Thirty-four and 19 student pharmacists completed the pharmacogenomics and genomic medicine courses, respectively, and 100% of eligible students (n=34) underwent genotyping. Student knowledge improved after the courses. Seventy-four percent (n=25) of students reported better understanding of pharmacogenomics based on having undergone genotyping. Completion of a novel pharmacogenomics elective course sequence that incorporated personal genotyping and genomic medicine was associated with increased student pharmacist knowledge and improved clinical confidence with pharmacogenomics.

摘要

评估个人基因分型和一种新型教育方法对学生关于药物基因组学和基因组医学的态度、知识及信念的影响。采用翻转课堂、以患者为中心的教学方法,为佛罗里达大学的药学专业学生提供了两门在线选修课程(药物基因组学和基因组医学)。在药物基因组学课程中,学生能够进行基因分型并将结果应用于患者案例。分别有34名和19名药学专业学生完成了药物基因组学和基因组医学课程,100%符合条件的学生(n = 34)进行了基因分型。课程结束后,学生的知识水平有所提高。74%(n = 25)的学生表示,基于进行了基因分型,对药物基因组学有了更好的理解。完成一门纳入个人基因分型和基因组医学的新型药物基因组学选修课程序列,与药学专业学生知识的增加以及对药物基因组学临床信心的提高相关。

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本文引用的文献

1
Evaluation of a shared pharmacogenomics curriculum for pharmacy students.药学专业学生共享药物基因组学课程的评估
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2
ASHP statement on the pharmacist's role in clinical pharmacogenomics.美国卫生系统药师协会关于临床药物基因组学中药剂师角色的声明。
Am J Health Syst Pharm. 2015 Apr 1;72(7):579-81. doi: 10.2146/sp150003.
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Misinterpretation of TPMT by a DTC genetic testing company.直接面向消费者的基因检测公司对 TPMT 的误读。
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6
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Am J Med Genet C Semin Med Genet. 2014 Mar;166C(1):56-67. doi: 10.1002/ajmg.c.31390. Epub 2014 Mar 10.
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Genome Med. 2013 Dec 30;5(12):113. doi: 10.1186/gm518. eCollection 2013.
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N C Med J. 2013 Nov-Dec;74(6):491-2.
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Evidence that personal genome testing enhances student learning in a course on genomics and personalized medicine.个人基因组检测增强了一门关于基因组学和个性化医学课程的学生学习效果的证据。
PLoS One. 2013 Jul 23;8(7):e68853. doi: 10.1371/journal.pone.0068853. Print 2013.
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Personal genotypes are teachable moments.个人基因型是可教育的时刻。
Genome Med. 2013 Mar 19;5(3):22. doi: 10.1186/gm426. eCollection 2013.