Cormier P, Mulner-Lorillon O, Ozon R, Bellé R
Physiologie de la Reproduction, CNRS URA 004, Paris.
Biosci Rep. 1989 Jun;9(3):351-8. doi: 10.1007/BF01114688.
In vivo beta casein phosphorylation was analysed in Xenopus full-grown oocytes arrested in the prophase of the meiotic cell division. The phosphorylation was inhibited by the protein kinase inhibitor (PKI) and also by heparin (3 micrograms/ml; final concentration). beta casein phosphorylation was increased by spermine (2 mM). Therefore, protein kinase A and casein kinase II are both active in vivo in full-grown oocytes and may be involved in the prophase arrest of meiotic cell division.