Obata Shumpei, Fujikawa Masato, Iwasaki Keisuke, Kakinoki Masashi, Sawada Osamu, Saishin Yoshitsugu, Kawamura Hajime, Ohji Masahito
Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Ophthalmic Res. 2017;57(2):135-140. doi: 10.1159/000448956. Epub 2016 Oct 20.
To investigate anatomic changes in retinal thickness (RT) and functional changes after vitrectomy for idiopathic epiretinal membranes (ERMs) with and without internal limiting membrane (ILM) peeling.
The medical records of 100 eyes of 96 patients with ERM who underwent vitrectomy and ERM removal were reviewed retrospectively. The RT was measured by optical coherence tomography, and the area was divided into 9 sections. The best-corrected visual acuity (BCVA), 9 RT areas, and incidence rates of recurrent ERM were compared between the groups with and without ILM peeling before the operation and 12 months postoperatively.
Thirty-nine eyes that underwent vitrectomy with ILM peeling and 61 eyes that underwent vitrectomy without ILM peeling met the inclusion criteria. There were no significant differences between the groups in the BCVA and any of the RTs before the operation and 12 months postoperatively. The ERMs recurred in 8 (20.5%) of 39 eyes and 26 (42.6%) of 61 eyes in the groups with and without ILM peeling, respectively, with a difference that reached significance (p = 0.02) 12 months postoperatively.
Vitrectomy for ERM affects the BCVA or the RTs 12 months postoperatively. Additional ILM peeling does not affect them, but it might reduce the ERM recurrence rate.
研究玻璃体切割术治疗伴有或不伴有内界膜（ILM）剥除的特发性视网膜前膜（ERM）后视网膜厚度（RT）的解剖学变化及功能变化。
回顾性分析96例接受玻璃体切割术并切除ERM的患者的100只眼的病历。通过光学相干断层扫描测量RT，并将区域分为9个部分。比较手术前和术后12个月有或没有ILM剥除组之间的最佳矫正视力（BCVA）、9个RT区域以及ERM复发率。
39只接受ILM剥除的玻璃体切割术眼和61只未接受ILM剥除的玻璃体切割术眼符合纳入标准。术前和术后12个月，两组之间的BCVA和任何RT均无显著差异。在有或没有ILM剥除的组中，ERM分别在39只眼中的8只（20.5%）和61只眼中的26只（42.6%）复发，术后12个月差异有统计学意义（p = 0.02）。
ERM的玻璃体切割术在术后12个月会影响BCVA或RT。额外的ILM剥除不会影响它们，但可能会降低ERM复发率。
