Takagi M, Sakota Y, Ishikawa G, Kamiyama R, Nakajima T, Nomura T
J Oral Surg. 1978 Aug;36(8):589-93.
A study was conducted of 16 patients with acute promyelocytic leukemia. The most common oral manifestations were hemorrhagic diathesis and leukemic involvement. There was gingival bleeding, petechiae, and ecchymosis of the oral mucosa, massive infiltration-induced gingival swelling, ulcerative glossitis, swelling of the tonsils, and facial palsy. Inflammatory stomatitis also occurred. Patients with acute promyelocytic leukemia had a higher incidence and severity of oral bleeding than those with other types of acute leukemia. However, the oral findings in our series were not necessarily specific for acute promyelocytic leukemia because the same oral symptoms occur in other forms of acute leukemia.
对16例急性早幼粒细胞白血病患者进行了一项研究。最常见的口腔表现为出血素质和白血病浸润。有牙龈出血、瘀点和口腔黏膜瘀斑、大量浸润引起的牙龈肿胀、溃疡性舌炎、扁桃体肿大及面神经麻痹。也发生了炎性口炎。急性早幼粒细胞白血病患者口腔出血的发生率和严重程度高于其他类型的急性白血病。然而，我们系列中的口腔表现不一定是急性早幼粒细胞白血病所特有的，因为其他形式的急性白血病也会出现相同的口腔症状。
