Xu R N
Zhonghua Wai Ke Za Zhi. 1989 Jan;27(1):28-30, 61.
Forty-three cases of male breast cancer treated in the past 3 decades, comprising 1.92% of total cases of breast cancer in both sexes during the same period, were analyzed. Local skin involvement occurred in half of the patients. 67.7% of the patients presented axillary lymph node metastases and 82.9% were in stage II and III. Non-infiltrative and infiltrative specific cancers were diagnosed in 2 cases each, and infiltrative non-specific in 39 cases. Retrospective determination of estrogen receptor (ER) and carcinoembryonic antigen (CEA) in 33 specimens revealed positive ER in 57.6% and positive CEA in 72.7%. The more advanced the clinical stage, the higher is the positive rate of ER. Cases with positive CEA usually carried a more invasive process and a poorer prognosis. Immunohistochemical investigation in male breast cancer patients was valuable in the selection of post-operative adjuvant endocrine therapy or chemotherapy. Postoperative rise in serum CEA in patients with positive CEA may indicate recurrence.
对过去30年中治疗的43例男性乳腺癌患者进行了分析，这些病例占同期两性乳腺癌总病例数的1.92%。半数患者出现局部皮肤受累。67.7%的患者出现腋窝淋巴结转移，82.9%处于II期和III期。非浸润性和浸润性特异性癌各诊断出2例，浸润性非特异性癌39例。对33份标本进行雌激素受体（ER）和癌胚抗原（CEA）的回顾性检测，结果显示ER阳性率为57.6%，CEA阳性率为72.7%。临床分期越晚，ER阳性率越高。CEA阳性的病例通常病程侵袭性更强，预后更差。对男性乳腺癌患者进行免疫组化检查，对于选择术后辅助内分泌治疗或化疗具有重要价值。CEA阳性患者术后血清CEA升高可能提示复发。
