Davis Kathryn M, Badu-Tawiah Abraham K
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, 43210, USA.
J Am Soc Mass Spectrom. 2017 Apr;28(4):647-654. doi: 10.1007/s13361-016-1516-8. Epub 2016 Oct 20.
The exposure of an aqueous-based liquid drop containing amines and graphite particles to plasma generated by a corona discharge results in heterogeneous aerobic dehydrogenation reactions. This green oxidation reaction occurring in ambient air afforded the corresponding quinolines and nitriles from tetrahydroquinolines and primary amines, respectively, at >96% yields in less than 2 min of reaction time. The accelerated dehydrogenation reactions occurred on the surface of a low energy hydrophobic paper, which served both as container for holding the reacting liquid drop and as a medium for achieving paper spray ionization of reaction products for subsequent characterization by ambient mass spectrometry. Control experiments indicate superoxide anions (O) are the main reactive species; the presence of graphite particles introduced heterogeneous surface effects, and enabled the efficient sampling of the plasma into the grounded analyte droplet solution. Graphical Abstract ᅟ.
将含有胺和石墨颗粒的水基液滴暴露于电晕放电产生的等离子体中会导致多相需氧脱氢反应。在环境空气中发生的这种绿色氧化反应分别从四氢喹啉和伯胺中以大于96%的产率在不到2分钟的反应时间内得到相应的喹啉和腈。加速的脱氢反应发生在低能量疏水纸的表面，该纸既作为容纳反应液滴的容器，又作为实现反应产物的纸喷雾电离以便随后通过常压质谱进行表征的介质。对照实验表明超氧阴离子（O）是主要的反应物种；石墨颗粒的存在引入了多相表面效应，并使等离子体能够有效地进入接地的分析物液滴溶液。图形摘要ᅟ。
