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2015年英国男男性行为者中产超广谱β-内酰胺酶及耐大环内酯类宋内志贺菌感染情况

ESBL-Producing and Macrolide-Resistant Shigella sonnei Infections among Men Who Have Sex with Men, England, 2015.

作者信息

Mook Piers, McCormick Jacquelyn, Bains Manpreet, Cowley Lauren A, Chattaway Marie A, Jenkins Claire, Mikhail Amy, Hughes Gwenda, Elson Richard, Day Martin, Manuel Rohini, Dave Jayshree, Field Nigel, Godbole Gauri, Dallman Timothy, Crook Paul

出版信息

Emerg Infect Dis. 2016 Nov;22(11):1948-1952. doi: 10.3201/eid2211.160653.

DOI:10.3201/eid2211.160653
PMID:27767929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5088027/
Abstract

In England in 2015, Shigella sonnei isolates from men who have sex with men produced extended-spectrum β-lactamases and exhibited macrolide resistance. Whole-genome sequencing showed a close relationship among the isolates, which harbored a plasmid that was previously identified in a shigellosis outbreak among this population but has acquired a mobile element.

摘要

2015年在英国，从男男性行为者中分离出的宋内志贺菌产生了超广谱β-内酰胺酶并表现出对大环内酯类药物的耐药性。全基因组测序显示这些分离株之间关系密切，它们携带一种质粒，该质粒先前在该人群的志贺菌病暴发中被鉴定出，但已获得了一个可移动元件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b407/5088027/c850b6b42361/16-0653-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b407/5088027/afb952b43da1/16-0653-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b407/5088027/c850b6b42361/16-0653-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b407/5088027/afb952b43da1/16-0653-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b407/5088027/c850b6b42361/16-0653-F2.jpg

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本文引用的文献

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Euro Surveill. 2015 Apr 16;20(15):21097. doi: 10.2807/1560-7917.es2015.20.15.21097.
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Epidemiol Infect. 2024 Oct 4;152:e115. doi: 10.1017/S0950268824001006.
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