Salama Tamer M S, Sabry Karim, Ghamrini Yaser El
a Department of Surgery , Abassia Faculty of Medicine, Ain Shams University , Nasr City, Cairo , Egypt.
J Invest Surg. 2017 Oct;30(5):291-296. doi: 10.1080/08941939.2016.1241841. Epub 2016 Oct 21.
Single anastomosis sleeve ileal bypass (SASI) procedure appears as a new metabolic and bariatric surgery based on Santoro's operation, in which a sleeve gastrectomy is followed by a side-to-side gastroileal anastomosis. The study is aimed to evaluate the short-term outcomes of laparoscopic single anastomosis sleeve ileal bypass with respect to postoperative weight loss and metabolic and nutritional effects on patients.
Forty-five morbidly obese patients with a mean age of 31.2 years and a mean body mass index (BMI) of 43.2 kg/m underwent SASI bypass. Postoperatively, all patients were followed up at 1, 3, 6, and 12 months, and during each visit data about their BMI, obesity-related comorbidities, and nutritional status were collected.
One year after the surgery, mean BMI decreased to 29.1 kg/m and there was significant decrease in plasma level of fasting blood glucose, insulin, and low-density lipoprotein. On the other hand, there was significant increase in high-density lipoprotein plasma level, whereas hemoglobin and albumin plasma level remained normal. Six months after the surgery, calcium plasma level showed mild decrease in two cases, which was improved with multivitamin tablets. In 93% of our patients, multivitamin supplements were stopped after six months of surgery.
Laparoscopic SASI bypass has been shown to be an effective, safe, and simple procedure for the treatment of morbid obesity and its associated metabolic consequences. Moreover, it results in minimal postoperative nutritional complications in comparison to other bariatric procedures.
单吻合口袖状回肠旁路术(SASI)是一种基于桑托罗手术的新型代谢减重手术,该手术先进行袖状胃切除术,然后进行端侧胃回肠吻合术。本研究旨在评估腹腔镜下单吻合口袖状回肠旁路术对患者术后体重减轻以及代谢和营养方面的短期效果。
45例平均年龄31.2岁、平均体重指数(BMI)为43.2kg/m²的病态肥胖患者接受了SASI旁路手术。术后,所有患者在1、3、6和12个月进行随访,每次随访时收集有关其BMI、肥胖相关合并症和营养状况的数据。
术后一年,平均BMI降至29.1kg/m²,空腹血糖、胰岛素和低密度脂蛋白的血浆水平显著下降。另一方面,高密度脂蛋白血浆水平显著升高,而血红蛋白和白蛋白血浆水平保持正常。术后六个月,有两例患者血钙水平轻度下降,通过服用多种维生素片得到改善。93%的患者在术后六个月后停止服用多种维生素补充剂。
腹腔镜SASI旁路术已被证明是一种有效、安全且简单的治疗病态肥胖及其相关代谢后果的手术。此外,与其他减重手术相比,它导致的术后营养并发症最少。