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Special considerations for antimicrobial therapy in the elderly.

作者信息

Norman D C

机构信息

UCLA School of Medicine.

出版信息

Geriatrics. 1989 Aug;44 Suppl A:23-7.

PMID:2777094
Abstract

The elderly are at increased risk of infection and suffer higher morbidity and mortality than younger people. Diagnosis of etiologic agents is frequently difficult. Alterations in pharmacokinetics in the elderly affect antibiotic choice. beta-lactam antibiotics and the fluoroquinolones are appropriate agents for the therapy of a wide range of infections in the elderly. Aminoglycosides should be used with caution in this age group due to the elderly's increased susceptibility to aminoglycoside-induced toxicity.

摘要

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