Morozumi Saori, Kato Shigenori, Yasui Keizo, Hasegawa Yasuhiro
Department of Neurology, Japanese Red Cross Nagoya Daini Hospital.
Rinsho Shinkeigaku. 2016 Nov 29;56(11):754-758. doi: 10.5692/clinicalneurol.cn-000907. Epub 2016 Oct 21.
We present the case of a 77-year-old man with a 10-year history of Parkinson disease (PD), who developed posterior reversible encephalopathy syndrome (PRES). We diagnosed the case as PRES based on clinical features and MRI findings. He experienced orthostatic hypotension and supine hypertension, including nocturnal hypertension. PRES may result from marked supine/nocturnal hypertension and fluctuation in blood pressure. In addition, exacerbated factors could be representative of neuroleptic malignant syndrome. The hypertensive effect of istradefylline should also not be excluded. We believe this is the first case report of a patient with PD developing PRES without vasopressor use.
我们报告了一例77岁男性帕金森病（PD）患者，其有10年病史，该患者出现了后部可逆性脑病综合征（PRES）。我们根据临床特征和MRI检查结果诊断该病例为PRES。他经历了体位性低血压和仰卧位高血压，包括夜间高血压。PRES可能由显著的仰卧位/夜间高血压和血压波动引起。此外，加重因素可能是神经源性恶性综合征的典型表现。也不应排除异他茶碱的升压作用。我们认为这是首例帕金森病患者在未使用血管升压药的情况下发生PRES的病例报告。
