Howard C P, Telander R L, Hoffman A D, Burgert E O
Mayo Clin Proc. 1978 Aug;53(8):538-41.
Hypertrophic osteoarthropathy in children is rare, especially when it is associated with lung metastsis. The patient reported herein had metastic osteogenic sarcoma and failed to respond to chemotherapy or thoractomy. There are several theories as to the pathogenesis of osteoarthropathy, but none is totally convincing. Vagotomy or transection of intercostal nerves has been advocated to relieve the symptoms of osteoarthropathy.
儿童肥大性骨关节病较为罕见,尤其是当它与肺转移相关时。本文报道的患者患有转移性骨肉瘤,对化疗或开胸手术均无反应。关于骨关节病的发病机制有多种理论,但没有一种完全令人信服。有人主张行迷走神经切断术或肋间神经横断术来缓解骨关节病的症状。