Kirazlı Özlem, Solmaz Bilgehan, Çavdar Safiye
* Department of Anatomy, School of Medicine, Marmara University, Istanbul, Turkey.
† Department of Neurosurgery, Istanbul Education and Research Hospital, Istanbul, Turkey.
J Integr Neurosci. 2016 Sep;15(3):337-345. doi: 10.1142/S0219635216500217. Epub 2016 Oct 24.
The dorsal column tracts (fasciculus gracilis and fasciculus cuneatus) are concerned with discriminative qualities of sensation. There are controversial descriptions related to the relations of dorsal column tracts with the dorsal horn laminae in text-books. The present study aims to define the laminae of the dorsal horn of the spinal cord that contribute fibers to the dorsal column tracts in the cervical, thoracic and lumbar spinal level. Series paraffin spinal cords sections of six formalin-embalmed adult human cadavers were evaluated. The present study shows that dorsal column tracts receive fiber contributions from laminae III and V and from Clarke's dorsal nucleus at varying spinal levels. At upper cervical levels (C1-C4) fiber contributions were from lamina V and few from lamina III, and at lower cervical levels (C5-C8) there were, in addition to these laminae, also contributions from the Clarke's dorsal nucleus. At upper thoracic levels (T1-T4) fiber contributions were from lamina V and few from Clarke's dorsal nucleus. At lower thoracic (T5-T12) and lumbar levels (L1-L5), in contrast, fiber contributions were only from Clarke's dorsal nucleus. The detailed knowledge of organization of the dorsal column tracts of the spinal cord may pave the way for future treatments of the spinal cord injuries.
薄束和楔束等后索传导束与感觉的辨别特性有关。在教科书中，关于后索传导束与脊髓后角板层的关系存在有争议的描述。本研究旨在确定脊髓后角的板层，这些板层在颈、胸和腰脊髓节段为后索传导束提供纤维。对六具用福尔马林防腐的成年人体尸体的系列石蜡脊髓切片进行了评估。本研究表明，后索传导束在不同脊髓节段接受来自板层III和V以及克拉克背核的纤维贡献。在颈上段（C1-C4），纤维来自板层V，来自板层III的较少；在颈下段（C5-C8），除了这些板层外，克拉克背核也有贡献。在胸上段（T1-T4），纤维来自板层V，来自克拉克背核的较少。相比之下，在胸下段（T5-T12）和腰段（L1-L5），纤维仅来自克拉克背核。对脊髓后索传导束组织结构的详细了解可能为未来脊髓损伤的治疗铺平道路。
