Fazio M, Vercellino V, Cavallero P, Sartoris S, Rodino A, Salassa B
Minerva Stomatol. 1978 Jan-Mar;27(1):23-7.
An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck. Complete (40.32%) and partial (43.55%) regressions were obtained relatively quickly. A satisfactory period of remission occurred in patients for whom no further treatment had seemed possible, either on account of the extent of the disease, or because surgery and/or radiotherapy had already been performed.
一种已成功用于治疗其他部位实体瘤的环磷酰胺、氟尿嘧啶和甲氨蝶呤联合用药方案，被用于治疗62例晚期头颈部肿瘤患者。相对较快地获得了完全缓解（40.32%）和部分缓解（43.55%）。对于那些因疾病范围或已经接受过手术和/或放疗而似乎无法进行进一步治疗的患者，出现了令人满意的缓解期。
