柳氮磺胺吡啶诱发一名类风湿关节炎患者出现免疫性血小板减少症。
Sulfasalazine induced immune thrombocytopenia in a patient with rheumatoid arthritis.
作者信息
Narayan Nehal, Rigby Shirley, Carlucci Francesco
机构信息
Nuffield Orthopaedic Centre, Headington, Oxford, UK.
Warwick Hospital, Warwick, UK.
出版信息
Clin Rheumatol. 2017 Feb;36(2):477-479. doi: 10.1007/s10067-016-3420-9. Epub 2016 Oct 24.
Abstract
Sulfasalazine has long been used for the treatment of rheumatoid arthritis and is often chosen as a first-line treatment. Here, we report a case of sulfasalazine-induced autoimmune thrombocytopenia and review the mechanisms behind drug-induced immune thrombocytopenia (DITP) and the approach to its diagnosis and management.
摘要
柳氮磺胺吡啶长期以来一直用于治疗类风湿性关节炎，并且常被选作一线治疗药物。在此，我们报告一例柳氮磺胺吡啶诱发的自身免疫性血小板减少症病例，并综述药物性免疫性血小板减少症（DITP）背后的机制及其诊断和管理方法。
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