Araujo Raphael L C, Riechelmann Rachel P, Fong Yuman
Department of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Department of Radiology and Oncology, Instituto do Câncer do Estado de São Paulo, University of São Paulo Medical School, São Paulo, Brazil.
J Surg Oncol. 2017 Feb;115(2):213-220. doi: 10.1002/jso.24482. Epub 2016 Oct 25.
Advances in surgery and chemotherapy regimens have increased the long-term survival of patients with colorectal liver metastases (CRLM). Although liver resection remains an essential part of any curative strategy for resectable CRLM, chemotherapy regimens have also improved the long-term outcomes. However, the optimal timing for chemotherapy regimens remains unclear. Thus, this review addressed key points to aid the decision-making process regarding the timing of chemotherapy and surgery for patients with resectable CRLM. J. Surg. Oncol. 2017;115:213-220. © 2016 Wiley Periodicals, Inc.
手术和化疗方案的进展提高了结直肠癌肝转移（CRLM）患者的长期生存率。尽管肝切除术仍然是可切除CRLM任何治愈性策略的重要组成部分，但化疗方案也改善了长期预后。然而，化疗方案的最佳时机仍不明确。因此，本综述阐述了关键要点，以协助制定关于可切除CRLM患者化疗和手术时机的决策过程。《外科肿瘤学杂志》2017年；115:213 - 220。©2016威利期刊公司。
