Suppr超能文献

污染伤口:清创术对降低细菌载量的有效性。

Contaminated wounds: Effectiveness of debridement for reducing bacterial load.

作者信息

Pomares G, Huguet S, Dap F, Dautel G

机构信息

Service de chirurgie plastique et reconstructrice de l'appareil locomoteur, centre chirurgical Émile-Gallé, CHU de Nancy, 49, rue Hermite, 54000 Nancy, France.

Service de chirurgie plastique et reconstructrice de l'appareil locomoteur, centre chirurgical Émile-Gallé, CHU de Nancy, 49, rue Hermite, 54000 Nancy, France.

出版信息

Hand Surg Rehabil. 2016 Sep;35(4):266-270. doi: 10.1016/j.hansur.2016.06.001. Epub 2016 Jul 15.

Abstract

Surgical management of contaminated hand wounds may seem anecdotal, but such injuries actually account for an appreciable amount of the activity in emergency hand centers, and recommendations put forward by scientific societies differ. Dealing effectively with this public health issue calls for clarifying the usefulness of the various available treatments. Our study's objective was to determine the effectiveness of surgical debridement. In this prospective study, 92 patients with contaminated hand wounds underwent surgical debridement. Selection criteria included the length of time between injury and treatment, and the mechanism of injury. Patients with infected wounds, those treated by antibiotics, who were immunosuppressed or had osteoarthritis were excluded. Skin samples were collected both before and after debridement. In 62% of cases, the wounds were contaminated before debridement. Following the procedure, 87% of the bacterial smears were negative. The comparison between debridement and smear results was statistically significant (Student's t test, P<0.001). Surgical debridement, with appropriate irrigation, can effectively eradicate bacterial flora due to contamination.

摘要

手部污染伤口的手术处理看似缺乏系统性论述,但这类损伤实际上在急诊手部中心的诊疗活动中占了相当比例,而且各科学学会提出的建议也不尽相同。要有效应对这一公共卫生问题,就需要明确各种现有治疗方法的有效性。我们这项研究的目的是确定手术清创的效果。在这项前瞻性研究中,92例手部污染伤口患者接受了手术清创。入选标准包括受伤至治疗的时间间隔以及受伤机制。排除有感染伤口的患者、接受抗生素治疗的患者、免疫功能低下或患有骨关节炎的患者。在清创前后均采集皮肤样本。在62%的病例中,伤口在清创前已被污染。手术后,87%的细菌涂片结果为阴性。清创与涂片结果之间的比较具有统计学意义(学生t检验,P<0.001)。手术清创配合适当冲洗,可有效清除因污染而产生的细菌菌群。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验