三维相位对比磁共振成像经验证可用于评估慢性血栓栓塞性肺动脉高压患者的肺动脉血流。
Three-dimensional phase contrast magnetic resonance imaging validated to assess pulmonary artery flow in patients with chronic thromboembolic pulmonary hypertension.
作者信息
Kawakubo Masateru, Akamine Hiroshi, Yamasaki Yuzo, Takemura Atsushi, Abe Kohtaro, Hosokawa Kazuya, Morishita Junji, Nagao Michinobu
机构信息
Department of Radiological Technology, Faculty of Fukuoka Medical Technology, Teikyo University, 6-22 Misaki-machi, Omuta, Fukuoka, Japan.
Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
出版信息
Radiol Phys Technol. 2017 Jun;10(2):249-255. doi: 10.1007/s12194-016-0383-0. Epub 2016 Oct 25.
In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson's correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.
在本研究中，一种新技术——三维相位对比磁共振成像（3D-PC MRI）被验证可用于评估慢性血栓栓塞性肺动脉高压（CTEPH）患者的肺动脉（PA）血流。对3例CTEPH患者治疗前后的3D-PC和二维相位对比（2D-PC）肺动脉磁共振数据进行了回顾性分析。此外，对5名健康志愿者进行了肺动脉的3D和2D-PC磁共振扫描。使用Pearson相关系数分析了通过3D-PC和2D-PC获得的每搏输出量（SV）的相关性。3D-PC和2D-PC在主肺动脉、左肺动脉和右肺动脉的SV之间存在极好的相关性（主肺动脉：r = 0.91，p < 0.01；左肺动脉：r = 0.72，p < 0.01；右肺动脉：r = 0.77，p < 0.01）。总之，3D-PC MRI能够准确量化CTEPH患者的肺动脉血流。
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