Takami Yoshinori, Yasuda Namie, Une Yumi
The Laboratory of Veterinary Pathology, School of Veterinary Medicine Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.
J Vet Med Sci. 2017 Jan 20;79(1):171-174. doi: 10.1292/jvms.16-0294. Epub 2016 Oct 27.
A penile tumor (4 × 2.5 × 1 cm) was surgically removed from an African pygmy hedgehog (Atelerix albiventris) aged 3 years and 5 months. The tumor was continuous with the dorsal fascia of the penile head. Histopathologically, tumor cells were pleomorphic (oval-, short spindle- and star-shaped cells) with low cell density. Abundant edematous stroma was weakly positive for Alcian blue staining and positive for colloidal iron reaction. Tumor cells displayed no cellular atypia or karyokinesis. Tumor cell cytoplasm was positive for vimentin antibody, while cytoplasm and nuclei were positive for S-100 protein antibody. Tumor cell ultrastructure matched that of fibroblasts, and the rough endoplasmic reticulum was enlarged. The tumor was diagnosed as myxoma. This represents the first report of myxoma in a hedgehog.
从一只3岁5个月大的非洲侏儒刺猬（Atelerix albiventris）身上手术切除了一个阴茎肿瘤（4×2.5×1厘米）。该肿瘤与阴茎头的背侧筋膜相连。组织病理学检查显示，肿瘤细胞多形性（椭圆形、短梭形和星形细胞），细胞密度低。丰富的水肿性间质对阿尔辛蓝染色呈弱阳性，对胶体铁反应呈阳性。肿瘤细胞未显示细胞异型性或核分裂象。肿瘤细胞胞质对波形蛋白抗体呈阳性，而胞质和细胞核对S-100蛋白抗体呈阳性。肿瘤细胞超微结构与成纤维细胞相符，粗面内质网扩大。该肿瘤被诊断为黏液瘤。这是刺猬黏液瘤的首次报道。
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