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一只非洲侏儒刺猬阴茎黏液纤维肉瘤——一例临床病例

Myxofibrosarcoma of the penis in an African pygmy hedgehog () - A clinical case.

作者信息

Kasalova Lucia, Cernochova Hana, Dvorakova Radka, Angelova Aneta, Knotek Zdenek

机构信息

Avian and Exotic Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czech Republic.

Department of Imaging Methods, Faculty of Veterinary Medicine, Dog and Cat Clinic, University of Veterinary Sciences Brno, Brno, Czech Republic.

出版信息

Vet Med (Praha). 2024 Apr 25;69(4):130-135. doi: 10.17221/107/2023-VETMED. eCollection 2024 Apr.

DOI:10.17221/107/2023-VETMED
PMID:38751990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11093646/
Abstract

A 3-year-old, 420 g, intact male African pygmy hedgehog () was presented with a sudden appearance of a mass protruding from its preputium. A detailed physical examination revealed the presence of a polyp-like mass, connected to the mucous membrane of the penis and a second, multilobular mass with a larger base. Both masses were surgically removed. While the histopathological examination of the polyp-like mass revealed only a chronic active inflammatory reaction, the histopathological examination of the multilobular mass revealed a tumorous tissue composed of spindle-shaped cells, irregularly oval or polygonal in some places. Focal tumour cells with a myxoid differentiation were observed in the greater part of this tumour. The stroma was made up of sparse fibrous tissue. The surface epithelium was hyperplastic with ulcerations and necrosis. The tumour was classified as a myxofibrosarcoma. Two weeks post-surgery, the patient did not show any clinical signs of the presented disease. According to our knowledge, this is the first published case of the surgical treatment of penile myxofibrosarcoma in an African pygmy hedgehog.

摘要

一只3岁、体重420克的完整雄性非洲侏儒刺猬被送来就诊,其阴茎突然出现一个肿物。详细的体格检查发现有一个息肉样肿物,与阴茎黏膜相连,还有一个基部较大的多叶状肿物。两个肿物均通过手术切除。息肉样肿物的组织病理学检查仅显示慢性活动性炎症反应,而多叶状肿物的组织病理学检查显示为肿瘤组织,由梭形细胞组成,有些地方呈不规则椭圆形或多边形。在该肿瘤的大部分区域观察到有黏液样分化的局灶性肿瘤细胞。间质由稀疏的纤维组织构成。表面上皮增生,伴有溃疡和坏死。该肿瘤被分类为黏液纤维肉瘤。术后两周,患者未表现出所患疾病的任何临床症状。据我们所知,这是首次发表的关于非洲侏儒刺猬阴茎黏液纤维肉瘤手术治疗的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/5fa428b0e084/VETMED-69-04-123107-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/082537257012/VETMED-69-04-123107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/9b4d295bbb00/VETMED-69-04-123107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/6fead67468b0/VETMED-69-04-123107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/23253e221a7b/VETMED-69-04-123107-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/0de81b2bdcf8/VETMED-69-04-123107-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/924154efd53e/VETMED-69-04-123107-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/801f5e9fbc4e/VETMED-69-04-123107-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/ae048e01401e/VETMED-69-04-123107-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/5fa428b0e084/VETMED-69-04-123107-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/082537257012/VETMED-69-04-123107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/9b4d295bbb00/VETMED-69-04-123107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/6fead67468b0/VETMED-69-04-123107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/23253e221a7b/VETMED-69-04-123107-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/0de81b2bdcf8/VETMED-69-04-123107-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/924154efd53e/VETMED-69-04-123107-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/801f5e9fbc4e/VETMED-69-04-123107-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/ae048e01401e/VETMED-69-04-123107-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8e/11093646/5fa428b0e084/VETMED-69-04-123107-g009.jpg

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本文引用的文献

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Surgical and medical management of an oral spindle cell sarcoma in an African hedgehog (Atelerix albiventris).非洲刺猬(Atelerix albiventris)口腔梭形细胞肉瘤的外科和医学治疗。
Vet Med Sci. 2022 May;8(3):1079-1084. doi: 10.1002/vms3.738. Epub 2022 Jan 25.
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Clinicopathologic Findings of Spontaneous Leukemia in 9 Pet African Hedgehogs ().9只宠物非洲刺猬自发性白血病的临床病理特征()
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Radiomic features from MRI distinguish myxomas from myxofibrosarcomas.
MRI 影像组学特征可区分黏液瘤和黏液纤维肉瘤。
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A retrospective study of disease incidence in African pygmy hedgehogs (Atelerix albiventris).对非洲侏儒刺猬(四趾刺猬)疾病发病率的回顾性研究。
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