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糖耐量异常人群中缺血性心脏病、动脉高血压和血脂异常的患病率

[Prevalence of ischemic heart disease, arterial hypertension and dyslipoproteinemia in persons with disorders of glucose tolerance].

作者信息

Suntsov Iu I, Kudriakova S V, Zhukovskiĭ G S, Mazovetskiĭ A G, Konstantinov V V

出版信息

Kardiologiia. 1989 Jun;29(6):32-5.

PMID:2779076
Abstract

Among 3490 males and females aged 20-69 years, oral glucose tolerance testing (GTT) revealed diabetes mellitus (DM) and abnormal glucose tolerance (AGT) in 94 and 401 persons, respectively. The prevalence of coronary heart disease (CHD), arterial hypertension (AH), and dyslipoproteinemias (DLP) was examined in groups of subjects that had normal GTT indices, patients with DM, and persons with AGT. In the latter, the prevalence of CHD was found to significantly higher than in those with normal GTT indices and be increased with severity of carbohydrate metabolic disturbances. The prevalence of AH did not drastically differ in persons with AGT and those with normal carbohydrate metabolism. The prevalence of DLP was significantly higher in subjects with AGT than in those with normal GTT values. It was also ascertained that DLP, as opposed to AH, was more meaningful as a risk factor for the development of CHD in persons with AGT and patients with DM.

摘要

在3490名年龄在20至69岁之间的男性和女性中,口服葡萄糖耐量试验(GTT)显示,分别有94人和401人患有糖尿病(DM)和葡萄糖耐量异常(AGT)。在GTT指标正常的受试者组、糖尿病患者组和AGT患者组中,对冠心病(CHD)、动脉高血压(AH)和血脂异常(DLP)的患病率进行了检查。在后者中,发现CHD的患病率显著高于GTT指标正常的人群,并且随着碳水化合物代谢紊乱的严重程度而增加。AGT患者和碳水化合物代谢正常的人之间AH的患病率没有显著差异。AGT受试者中DLP的患病率显著高于GTT值正常的受试者。还确定,与AH不同,DLP作为AGT患者和糖尿病患者发生CHD的危险因素更有意义。

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