Barinov V G, Bogomolov B P, Deviatkin A V, Shvedova L P
Klin Med (Mosk). 1989 Jun;67(6):104-7.
Data are given on the changes in the hemostatic system in 42 patients with uncomplicated influenza and in complications (pneumonia, bronchitis, aggravation of ischemic heart disease). In the acute period of the disease they were characterized by hypercoagulation which was most pronounced in patients with influenza complicated by pneumonia. In cases of aggravation of ischemic heart disease functional platelet activity during convalescence decreases but the plasma link of hemostasis remains activated and fibrinolytic blood activity inhibited. Functional platelet activity in dynamics of the disease increases which should be taken into consideration in pathogenetic therapy.
给出了42例无并发症流感患者以及出现并发症(肺炎、支气管炎、缺血性心脏病加重)患者止血系统的变化数据。在疾病急性期,其特征为高凝状态,在并发肺炎的流感患者中最为明显。在缺血性心脏病加重的病例中,恢复期血小板功能活性降低,但止血的血浆环节仍处于激活状态,血液纤溶活性受到抑制。疾病动态过程中血小板功能活性增加,这在发病机制治疗中应予以考虑。