Andriukin A A, Kodolova I M, Marinin V F, Evseeva L V
Klin Med (Mosk). 1989 Jun;67(6):122-5.
Description is given of 11 patients with a severe form of protracted corticosteroid-dependent asthma. They died in status asthmaticus. Most of these patients had protracted status asthmaticus and cardiopulmonary failure. Pneumonia with toxic liver and kidney affection developed in some of them in parallel with glucocorticoid therapy. Long-term glucocorticoid treatment may give rise to vasculitis and thromboembolism of the pulmonary trunk. The principal disease can be aggravated by infection, administration of histoglobin, decrease in the dose of glucocorticosteroids or their discontinuation.
描述了11例严重型持续性糖皮质激素依赖型哮喘患者。他们死于哮喘持续状态。这些患者大多患有持续性哮喘持续状态和心肺衰竭。其中一些患者在接受糖皮质激素治疗的同时并发了伴有中毒性肝肾损害的肺炎。长期糖皮质激素治疗可能导致血管炎和肺动脉主干血栓栓塞。感染、给予组织血红蛋白、糖皮质激素剂量减少或停药可加重原发性疾病。