Arriola-Villalobos P, Almendral-Gómez J, Garzón N, Ruiz-Medrano J, Fernández-Pérez C, Martínez-de-la-Casa J M, Díaz-Valle D
Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Calle del Prof. Martín Lagos, s/n, 28040 Madrid, Spain.
Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Calle del Prof. Martín Lagos, s/n, 28040 Madrid, Spain.
J Fr Ophtalmol. 2016 Dec;39(10):859-865. doi: 10.1016/j.jfo.2016.09.003. Epub 2016 Oct 25.
To determine whether pupil dilation affects biometric measurements and intraocular lens (IOL) power calculation made using the new swept-source optical coherence tomography-based optical biometer (IOLMaster 700; Carl Zeiss Meditec, Jena, Germany).
Eighty-one eyes of 81 patients evaluated for cataract surgery were prospectively examined using the IOLMaster 700 before and after pupil dilation with tropicamide 1%. The measurements made were: axial length (AL), central corneal thickness (CCT), aqueous chamber depth (ACD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW) and pupil diameter (PD). Holladay II and SRK/T formulas were used to calculate IOL power. Agreement between measurement modes (with and without dilation) was assessed through intraclass correlation coefficients (ICC) and Bland-Altman plots.
Mean patient age was 75.17±7.54 years (range: 57-92). Of the variables determined, CCT, ACD, LT and WTW varied significantly according to pupil dilation. Excellent intraobserver correlation was observed between measurements made before and after pupil dilation. Mean IOL power calculation using the Holladay 2 and SRK/T formulas were unmodified by pupil dilation.
The use of pupil dilation produces statistical yet not clinically significant differences in some IOLMaster 700 measurements. However, it does not affect mean IOL power calculation.
确定瞳孔散大是否会影响使用新型基于扫频源光学相干断层扫描的光学生物测量仪（IOLMaster 700；德国耶拿卡尔蔡司医疗技术公司）进行的生物测量和人工晶状体（IOL）度数计算。
对81例接受白内障手术评估的患者的81只眼睛，在使用1%托吡卡胺散瞳前后，使用IOLMaster 700进行前瞻性检查。测量的参数包括：眼轴长度（AL）、中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）、平均角膜曲率（MK）、白对白距离（WTW）和瞳孔直径（PD）。使用Holladay II和SRK/T公式计算IOL度数。通过组内相关系数（ICC）和Bland-Altman图评估测量模式（散瞳和未散瞳）之间的一致性。
患者平均年龄为75.17±7.54岁（范围：57 - 92岁）。在所测定的变量中，CCT、ACD、LT和WTW根据瞳孔散大情况有显著变化。在散瞳前后的测量之间观察到了极好的观察者内相关性。使用Holladay 2和SRK/T公式计算的平均IOL度数不受瞳孔散大的影响。
瞳孔散大在一些IOLMaster 700测量中产生了统计学上但无临床意义的差异。然而，它不影响平均IOL度数计算。
