Department of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Department of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Science, Chinese University of Hong Kong, Hong Kong, China.
Gastroenterology. 2017 Feb;152(2):313-321.e2. doi: 10.1053/j.gastro.2016.10.020. Epub 2016 Oct 25.
The inflammatory bowel diseases (IBDs) are contemporary conditions of industrialized societies. The prevalence of IBD continues to increase steadily in Western countries, and newly industrialized countries have a rapidly increasing incidence. The global spread of IBD appears to associate with Westernization of diets and environments, which affects the intestinal microbiome and increases the risk of IBD in genetically susceptible individuals. It is important to increase our understanding of these events to slow progression of IBD. We present a long-term plan to develop interventions that slow or stop the global increase in the incidence of IBD.
炎症性肠病（IBD）是现代工业化社会的病症。在西方国家，IBD 的患病率持续稳步上升，新兴工业化国家的发病率也在迅速上升。IBD 在全球的传播似乎与饮食和环境的西化有关，这影响了肠道微生物组，并增加了遗传易感个体患 IBD 的风险。重要的是要增加我们对这些事件的了解，以减缓 IBD 的进展。我们提出了一个长期计划，以制定干预措施，减缓或阻止 IBD 发病率在全球范围内的增长。
