2008 - 2014年福建省手足口病的流行病学与病因学
Epidemiology and etiology of hand, foot, and mouth disease in Fujian province, 2008-2014.
作者信息
Weng Yuwei, Chen Wei, Huang Meng, He Wenxiang, Zheng Kuicheng, Yan Yansheng
机构信息
Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.
Public Health School of Fujian Medical University, Fuzhou, 350004, Fujian, China.
出版信息
Arch Virol. 2017 Feb;162(2):535-542. doi: 10.1007/s00705-016-3127-x. Epub 2016 Oct 28.
Millions of cases of hand, foot, and mouth disease (HFMD) have been reported annually in mainland China since 2008. In this study, we investigated the epidemiology and etiology of an HFMD epidemic in Fujian province, which is located in subtropical southeastern China. Our study found similar epidemiological features of HFMD in southern areas of China, including seasonality and demographic distribution, as well as correlation between severity of illness and serotype. At least 22 serotypes of other enterovirus co-circulating with enterovirus 71 were found to belong to clade C4a, and those circulating with coxsackievirus A16 were associated with clades B1a and B1b.
自2008年以来，中国大陆每年报告数百万例手足口病（HFMD）病例。在本研究中，我们调查了位于中国东南部亚热带地区的福建省手足口病疫情的流行病学和病因。我们的研究发现，中国南方手足口病具有相似的流行病学特征，包括季节性和人口分布，以及疾病严重程度与血清型之间的相关性。发现至少22种与肠道病毒71型共同流行的其他肠道病毒血清型属于C4a进化枝，与柯萨奇病毒A16共同流行的血清型与B1a和B1b进化枝相关。
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