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服务重新设计对急性心肌梗死患者血管重建率社会经济不平等的影响:一项自然实验和电子记录关联队列研究

Impact of service redesign on the socioeconomic inequity in revascularisation rates for patients with acute myocardial infarction: a natural experiment and electronic record-linked cohort study.

作者信息

Evans Lloyd W, van Woerden Hugo, Davies Gareth R, Fone David

机构信息

Public Health Wales Observatory, Public Health Wales, Carmarthen, UK.

NHS Highland, Inverness, UK.

出版信息

BMJ Open. 2016 Oct 24;6(10):e011656. doi: 10.1136/bmjopen-2016-011656.

Abstract

AIM

To investigate the impact of service redesign in the provision of revascularisation procedures on the historical socioeconomic inequity in revascularisation rates for patients with acute myocardial infarction (AMI).

DESIGN

Natural experiment and retrospective cohort study using linked data sets in the Secure Anonymised Information Linkage databank.

NON-RANDOMISED INTERVENTION: An increase in the capacity of revascularisation procedures and service redesign in the provision of revascularisation in late 2011 to early 2012.

SETTING

South Wales cardiac network, Census 2011 population 1 359 051 aged 35 years and over.

PARTICIPANTS

9128 participants admitted to an NHS hospital with a first AMI between 1 January 2010 and 30 June 2013, with 6-months follow-up.

MAIN OUTCOME MEASURE

Hazard ratios (HRs) for the time to revascularisation for deprivation quintiles, age, gender, comorbidities, rural-urban classification and revascularisation facilities of admitting hospital.

RESULTS

In the preintervention period, there was a statistically significant decreased adjusted risk of revascularisation for participants in the most deprived quintile compared to the least deprived quintile (HR 0.80; 95% CI 0.69 to 0.92, p=0.002). In the postintervention period, the increase in revascularisation rates was statistically significant in all quintiles, and there was no longer any statistically significant difference in the adjusted revascularisation risk between the most and the least deprived quintile (HR 1.04; 95% CI 0.89 to 1.20, p<0.649). However, inequity persisted for those aged 75 years and over (HR 0.40; 95% CI 0.35 to 0.46, p<0.001) and women (HR 0.77; 95% CI 0.70 to 0.86, p<0.001).

CONCLUSIONS

Socioeconomic inequity of access to revascularisation was no longer apparent following redesign of revascularisation services in the south Wales cardiac network, although inequity persisted for women and those aged 75+ years. Increasing the capacity of revascularisation did not differentially benefit participants from the least deprived areas.

摘要

目的

研究血管重建手术服务重新设计对急性心肌梗死(AMI)患者血管重建率方面历史社会经济不平等的影响。

设计

利用安全匿名信息链接数据库中的关联数据集进行自然实验和回顾性队列研究。

非随机干预

2011年末至2012年初增加血管重建手术的能力并对血管重建服务进行重新设计。

背景

南威尔士心脏网络,2011年人口普查中35岁及以上人口为1 359 051人。

参与者

2010年1月1日至2013年6月30日期间因首次急性心肌梗死入住国民健康服务(NHS)医院且随访6个月的9128名参与者。

主要观察指标

根据贫困五分位数、年龄、性别、合并症、城乡分类以及收治医院的血管重建设施,计算血管重建时间的风险比(HRs)。

结果

在干预前期,与最不贫困五分位数的参与者相比,最贫困五分位数的参与者经调整后的血管重建风险显著降低(HR 0.80;95%置信区间0.69至0.92,p = 0.002)。在干预后期,所有五分位数的血管重建率均有显著提高,最贫困和最不贫困五分位数之间经调整后的血管重建风险不再有显著差异(HR 1.04;95%置信区间0.89至1.20,p < 0.649)。然而,75岁及以上人群(HR 0.40;95%置信区间0.35至0.46,p < 0.001)和女性(HR 0.77;95%置信区间0.70至0.86,p < 0.001)的不平等现象仍然存在。

结论

南威尔士心脏网络对血管重建服务进行重新设计后,血管重建可及性方面的社会经济不平等不再明显,尽管女性和75岁及以上人群的不平等现象仍然存在。增加血管重建能力并没有使最不贫困地区的参与者获得更多益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/705d/5093375/19e3d9ba323a/bmjopen2016011656f01.jpg

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