Rohlffs Fiona, Tsilimparis Nikolaos, Saleptsis Vasilis, Diener Holger, Debus E Sebastian, Kölbel Tilo
1 German Aortic Center, University Heart Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
J Endovasc Ther. 2017 Feb;24(1):84-88. doi: 10.1177/1526602816675621. Epub 2016 Oct 26.
To investigate the amount of gas released from Zenith thoracic stent-grafts using standard saline flushing vs the carbon dioxide flushing technique.
In an experimental bench setting, 20 thoracic stent-grafts were separated into 2 groups of 10 endografts. One group of grafts was flushed with 60 mL saline and the other group was flushed with carbon dioxide for 5 minutes followed by 60 mL saline. All grafts were deployed into a water-filled container with a curved plastic pipe; the deployment was recorded and released gas was measured using a calibrated setup.
Gas was released from all grafts in both study groups during endograft deployment. The average amount of released gas per graft was significantly lower in the study group with carbon dioxide flushing (0.79 vs 0.51 mL, p=0.005).
Thoracic endografts release significant amounts of air during deployment if flushed according to the instructions for use. Application of carbon dioxide for the flushing of thoracic stent-grafts prior to standard saline flush significantly reduces the amount of gas released during deployment. The additional use of carbon dioxide should be considered as a standard flush technique for aortic stent-grafts, especially in those implanted in proximal aortic segments, to reduce the risk of air embolism and stroke.
研究使用标准盐水冲洗与二氧化碳冲洗技术时，Zenith胸主动脉覆膜支架释放的气体量。
在实验台上，将20个胸主动脉覆膜支架分成两组，每组10个。一组用60毫升盐水冲洗，另一组先用二氧化碳冲洗5分钟，然后再用60毫升盐水冲洗。所有支架被置入一个装有弯曲塑料管的盛水容器中；记录支架释放过程并使用校准装置测量释放的气体。
在两组研究中，所有支架在释放过程中均有气体释放。二氧化碳冲洗组每个支架的平均气体释放量显著更低（0.79对0.51毫升，p = 0.005）。
如果按照使用说明冲洗，胸主动脉覆膜支架在释放过程中会释放大量空气。在标准盐水冲洗之前使用二氧化碳冲洗胸主动脉覆膜支架可显著减少释放过程中的气体量。应考虑将额外使用二氧化碳作为主动脉覆膜支架的标准冲洗技术，尤其是对于植入主动脉近端节段的支架，以降低空气栓塞和中风的风险。
