Karzijn Renata, Alberts Leonie, Kelder Johannes C, Hofman Frederik N, El Sharouni Sherif Y, Kastelijn Elisabeth A, Schramel Franz M N H
Department of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.
Department of Epidemiology and Statistics, St. Antonius Hospital, Nieuwegein, the Netherlands.
Anticancer Res. 2016 Oct;36(10):5413-5418. doi: 10.21873/anticanres.11118.
BACKGROUND/AIM: Patients treated for early-stage non-small cell lung cancer (NSCLC) need post-treatment surveillance for detecting recurrence of disease. The aim of this study was to provide evidence for the appropriate follow-up.
The overall survival (OS), 1- and 3-year survival and progression-free survival (PFS) were retrospectively compared between two imaging modality groups. One group received only chest radiographs (CR group) and one group received chest radiographs and at least one computed tomography scan (CT group).
Patients in the CR group (n=50) had no inferior OS (hazard ratio (HR)=1.427, 95% confidence interval (CI)=0.755-2.695, p=0.273) and PFS (HR=1.156, 95% CI=0.645-2.069, p=0.627) compared to patients in the CT group (n=23). Both 1- and 3-year survival were equal in the two groups (HR=5.544, 95% CI=0.530-58.031, p=0.153 and HR=1.540, 95% CI=0.752-3.154, p=0.238, respectively).
Follow-up with a chest radiography did not result in inferior clinical outcomes compared to follow-up with a CT scan.
背景/目的：早期非小细胞肺癌（NSCLC）患者在接受治疗后需要进行疾病复发监测。本研究旨在为适当的随访提供依据。
回顾性比较了两个影像学检查方式组的总生存期（OS）、1年和3年生存率以及无进展生存期（PFS）。一组仅接受胸部X光片检查（CR组），另一组接受胸部X光片检查并至少进行一次计算机断层扫描（CT组）。
与CT组（n = 23）患者相比，CR组（n = 50）患者的总生存期（风险比（HR）= 1.427，95%置信区间（CI）= 0.755 - 2.695，p = 0.273）和无进展生存期（HR = 1.156，95% CI = 0.645 - 2.069，p = 0.627）并无劣势。两组的1年和3年生存率均相等（HR分别为5.544，95% CI = 0.530 - 58.031，p = 0.153；HR为1.540，95% CI = 0.752 - 3.154，p = 0.238）。
与CT扫描随访相比，胸部X光片随访并未导致临床结果更差。
