Fujita Y, Nakamura Y, Sakata K, Hara N, Kobayashi M, Nagai M, Yanagawa H, Kawasaki T
Department of Public Health, Jichi Medical School, Tochigi-ken, Japan.
Pediatrics. 1989 Oct;84(4):666-9.
The rate of second-case Kawasaki disease occurring among 1788 siblings of children with the disease was derived from data obtained from questionnaires mailed to the members of the Japanese Association of Parents of Children With Kawasaki Disease. Within 1 year after the onset of the first case in a family, the overall second-case rate was 2.1% for siblings, as compared to an overall incidence of approximately 0.19% in the general population of children 0 to 4 years of age in Japan in the epidemic year 1982. For siblings younger than 1 year of age, it was 8.4%, and for those between 1 and 2 years of age, it was 9.3%. More than half (54.1%) of the second cases developed 10 days or less after the first cases occurred.
1788名川崎病患儿的兄弟姐妹中出现第二例川崎病的比率，来自于邮寄给日本川崎病患儿家长协会成员的调查问卷所获数据。在一个家庭中首例发病后的1年内，兄弟姐妹中第二例的总体发生率为2.1%，相比之下，在1982年疫情期间日本0至4岁儿童的总人口中，总体发病率约为0.19%。1岁以下的兄弟姐妹发生率为8.4%，1至2岁的为9.3%。超过半数（54.1%）的第二例在第一例发病后10天或更短时间内出现。
