Penna Vincenzo, Stark G Bjoern, Iblher Niklas
From the Department of Plastic and Hand Surgery, University of Freiburg Medical Center, Freiburg, Germany.
Ann Plast Surg. 2017 Mar;78(3):334-337. doi: 10.1097/SAP.0000000000000931.
Although aging changes of the female perioral region and aesthetic procedures for perioral rejuvenation are described in literature, specific data for the male population are lacking. This study aims to evaluate perioral aging process in the male population to compare quality and quantity of the observed changes to the female population.
Magnetic resonance imaging (MRI) scans of 22 male subjects, were recruited into 2 age groups: young (20-35 years) and old (65-80 years) and the following parameters were measured: length of visible upper lip, thickness of upper lip at the level of vermilion border, thickness of upper lip at the level of the mid lip, and cross-section area of upper lip. Cadaver transverse sections of the upper lip of 10 individuals in 2 age groups, young (<40 years, n = 5) and old (>80 years, n = 5) underwent histological analysis of the relevant anatomical structures.
The MRI analyses does not show a statistically significant difference in upper lip lengths of old and young subjects (P = 0.213). Upper lip thickness decreases statistically significant (P < 0.001), the midline sagittal upper lip area does not show a significant change (P = 0.57). Histomorphometry shows a statistically significant decrease of cutis thickness, increase of subcutaneous fat, thinning of the orbicularis muscle, and a broadening of the orbicularis oris angle.
The aging changes of the perioral region in men and women are similar in regard to the general processes, yet the extent of the changes is less striking in the men.
尽管文献中描述了女性口周区域的衰老变化及口周年轻化的美学手术，但缺乏男性人群的具体数据。本研究旨在评估男性人群的口周衰老过程，以比较观察到的变化与女性人群在质量和数量上的差异。
招募了22名男性受试者进行磁共振成像（MRI）扫描，分为2个年龄组：年轻组（20 - 35岁）和老年组（65 - 80岁），并测量以下参数：可见上唇长度、唇红缘水平处上唇厚度、唇中部水平处上唇厚度以及上唇横截面积。对2个年龄组（年轻组<40岁，n = 5；老年组>80岁，n = 5）的10名个体的上唇尸体横切片进行相关解剖结构的组织学分析。
MRI分析显示老年和年轻受试者的上唇长度无统计学显著差异（P = 0.213）。上唇厚度有统计学显著下降（P < 0.001），中线矢状面上唇面积无显著变化（P = 0.57）。组织形态计量学显示，表皮厚度有统计学显著下降，皮下脂肪增加，眼轮匝肌变薄，口轮匝肌角度变宽。
男性和女性口周区域的衰老变化在一般过程方面相似，但男性变化程度不那么明显。
