Spoldi Elisa, Schwarz Tobias, Sabattini Silvia, Vignoli Massimo, Cancedda Simona, Rossi Federica
Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL, 32610.
Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, University of Edinburgh, Roslin, Midlothian, Scotland, UK.
Vet Radiol Ultrasound. 2017 Jan;58(1):29-37. doi: 10.1111/vru.12445. Epub 2016 Nov 1.
A better understanding of the CT features of different forms of canine and feline adipose tumors would be valuable for improving patient management and treatment. The purpose of this retrospective, cross-sectional study was to describe and compare the CT features of pathologically confirmed lipomas, infiltrative lipomas, and liposarcomas in a sample of canine and feline patients. A total of 50 animals (46 dogs, four cats) and a total of 60 lesions (23 lipomas, 20 infiltrative lipomas, and 17 liposarcomas) were included in the study. Lipomas appeared as round to oval-shaped (n = 21), well-marginated (n = 20) fat-attenuating lesions. Infiltrative lipomas appeared as homogeneous, fat-attenuating masses but, unlike lipomas, they were most commonly characterized by an irregular shape (75%; P < 0.001), and linear components, hyperattenuating relative to the surrounding fat (100%; P < 0.05). Liposarcomas were represented exclusively by heterogeneous lesions with soft tissue attenuating components with a multinodular appearance (76.5%; P < 0.05). Regional lymphadenopathy (n = 10) and amorphous mineralization (n = 4) were also observed in association with liposarcomas. Computed tomography can provide useful information regarding disease location, extent, and involvement of the adjacent structures. Tumor definition and shape were the most useful parameters to differentiate between lipomas and infiltrative lipomas. The presence of a heterogeneous mass, with a multinodular soft tissue component and associated regional lymphadenopathy and mineralization, were features favoring a diagnosis of liposarcoma.
更好地了解犬猫不同类型脂肪肿瘤的CT特征，对于改善患者管理和治疗具有重要价值。这项回顾性横断面研究的目的是描述和比较经病理证实的犬猫脂肪瘤、浸润性脂肪瘤和脂肪肉瘤的CT特征。该研究共纳入50只动物（46只狗，4只猫）和60个病灶（23个脂肪瘤、20个浸润性脂肪瘤和17个脂肪肉瘤）。脂肪瘤表现为圆形至椭圆形（n = 21）、边界清晰（n = 20）的脂肪密度病灶。浸润性脂肪瘤表现为均匀的脂肪密度肿块，但与脂肪瘤不同的是，它们最常见的特征是形状不规则（75%；P < 0.001），以及相对于周围脂肪呈高密度的线性成分（100%；P < 0.05）。脂肪肉瘤仅表现为具有软组织密度成分的不均匀病灶，呈多结节状外观（76.5%；P < 0.05）。还观察到与脂肪肉瘤相关的区域淋巴结肿大（n = 10）和无定形钙化（n = 4）。计算机断层扫描可以提供有关疾病位置、范围以及相邻结构受累情况的有用信息。肿瘤的界定和形状是区分脂肪瘤和浸润性脂肪瘤最有用的参数。存在不均匀肿块、多结节状软组织成分以及相关的区域淋巴结肿大和钙化，是支持脂肪肉瘤诊断的特征。
