Freund Brin, Mowry Ellen M, Levy Michael, Newsome Scott D
Department of Neurology, Johns Hopkins University, Baltimore, MD, United States.
Department of Neurology, Johns Hopkins University, Baltimore, MD, United States.
J Neuroimmunol. 2016 Nov 15;300:18-20. doi: 10.1016/j.jneuroim.2016.10.005. Epub 2016 Oct 12.
Neuromyelitis optica spectrum disorder (NMO-SD) and spinal dural arteriovenous fistula (SDAVF) can both cause longitudinally extensive myelopathy. We describe a case of longitudinally extensive myelopathy attributed to a SDAVF. Despite treatment, myelopathy recurred and led to subsequent NMO-SD diagnosis. We consider a possible link between the two disorders which may shed light on the pathophysiology of NMO-SD. To our knowledge, this is the first published case of co-existent NMO-SD and SDAVF leading to myelopathy.
视神经脊髓炎谱系障碍(NMO-SD)和硬脊膜动静脉瘘(SDAVF)均可导致长节段脊髓病变。我们描述了一例由SDAVF引起的长节段脊髓病变病例。尽管进行了治疗,但脊髓病变仍复发,并导致随后的NMO-SD诊断。我们考虑这两种疾病之间可能存在的联系,这可能有助于阐明NMO-SD的病理生理学。据我们所知,这是首例关于NMO-SD和SDAVF并存导致脊髓病变的报道病例。